Continuous Renal Replacement Therapy (crrt): Consider Delayed Administration Of Concurrent Echinocandins, Such As Caspofungin, To Reduce The Risk Of Adsorption Onto New Polyacrylonitrile (pan)-based F
Recall Summary Caspofungin, an antifungal medication, can bind to certain types of filters used in continuous kidney replacement therapy (CRRT), potentially reducing the medication's effectiveness. This affects patients in the United Kingdom who need both CRRT and caspofungin treatment simultaneously. Healthcare providers are being advised to consider timing the administration of caspofungin separately from CRRT to prevent this interaction.
- Recalling firm
- Consider delayed administration of concurrent echinocandins
- Reason
- Continuous renal replacement therapy (CRRT) is used for managing severe acute kidney injury and fluid overload. Published evidence has shown that caspofungin can bind to polyacrylonitrile (PAN)-based membranes used in CRRT which may result in ineffective antifungal treatment.
- Classification
- Unclassified
- Category
- drug recall
- Country
- United Kingdom
- Agency
- UK Medicines and Healthcare products Regulatory Agency
- Recall date
- 2026-10-13
- Status
- Ongoing
- Distribution
- United Kingdom
Official recall notice from UK Medicines and Healthcare products Regulatory Agency
Recall details on Nibble Recalls: https://trynibble.app/recalls/794c22a2-9556-459b-a3b6-51a24efcfbf4